Drugs that target and reduce arthritis symptoms and treat arthritis’ debilitating effects and deterioration processes are developed.
Osteoarthritis is the most common form of arthritis. It can include damage to the joints of the hips, knees and wrists. Although usually diagnosed in older people, people as young as 25 can develop osteoarthritis in combination.
There is no cure for this disease and medical treatments can provide relief of symptoms and improvement in quality of life. This disease takes its toll on physical activity that leads to disability, but more and more dependency on others to walk and climb stairs.
For effectively reduce pain and inflammation in affected joints traditional medical treatment with anti-inflammatory medicines called NSAIDs. These are not steroids, however, the patients have been found long-term treatment with these drugs to cause serious side effects, and internal bleeding, high blood pressure (hypertension), heart (heart attack) and damage to the kidneys.
rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis are chronic joint diseases. Drugs to treat these serious types of arthritis are aimed to stop, prevent and even reverse bone and cartilage changes come as the disease worsens.
Rheumatoid arthritis is an example of destructive arthritis. This progressive disease causes inflammation in the joints. Continuing the process of inflammation attacks the bones membrane causes bone erosion often leads to irreversible joint damage. This inflammatory condition can lead to significant disability and have significant joint pain. The severity of this bone structure damage can be predicted according to the severity of inflammation, the number of swollen joints or duration of morning stiffness. Bone and cartilage damage is a fast and dynamic after disease onset. In most patients this structural change in bone loss in the first year of the disease. It takes the key to successful treatment of the first analysis.
To handle this process by effectively control inflation and reverse the damage to the bone, the specific drugs developed. These are known as regular Disease-rheumatic drugs or disease modifying antirheumatic drugs.
spondylitis other chronic joint disease involves inflammation of the sacroiliac joints and spine. As the disease progresses the patient suffering from ongoing back pain stiffness. Medications for ankylosing spondylitis are physiotherapy and drugs NSAIDs (NSAIDs).
Psoriatic arthritis patients in addition to inflammatory arthritis process also suffer from psoriasis on their skin. In most cases, they become the first psoriasis which later worsened to psoriatic arthritis, although in some patients psoriasis symptoms occurred after the development of arthritis disease. In addition to arthritis and psoriasis on their skin, these patients often also have changes in their nails as pitting or ridging. This disease also leads to severe joint damage and disability overtime.
latest drugs developed to treat these three chronic joint disease rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis is called Tumor necrosis factor alpha blockers (TNF α-blockers). These are biologically specific treatments that have really revolutionized the treatment of inflammatory arthritis diseases effectively control their symptoms and progression.
depends on if the patient can be treated with TNF alpha blockers or in what is called combination with disease modifying anti-rheumatic drugs (DMARD therapy). While TNF alpha blockers are very effective in treating the disease, especially if treatment begins at the beginning of the disease, this treatment often causes side effects and the development of serious infections requiring hospitalization.